NUDT1 cDNA

NuDT1 is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP, 8-oxo-dATP, 2-hydroxy-dATP, and 2-hydroxy rATP, to monophosphates, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. It is localized mainly in the cytoplasm, with some in the mitochondria, suggesting that it is involved in the sanitization of nucleotide pools both for nuclear and mitochondrial genomes. And this protein expressed at much higher levels in proliferating cells than in resting cells

Product Specifications

Product Name Alternative

MTH1

Chromosomal Location

7p22

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGGGCGCCT CCAGGCTCTA TACCCTGGTG CTGGTCCTGC AGCCTCAGCG AGTTCTCCTG GGCATGAAAA AGCGAGGCTT CGGGGCCGGC CGGTGGAATG GCTTTGGGGG CAAAGTGCAA GAAGGAGAGA CCATCGAGGA TGGGGCTAGG AGGGAGCTGC AGGAGGAGAG CGGTCTGACA GTGGACGCCC TGCACAAGGT GGGCCAGATC GTGTTTGAGT TCGTGGGCGA GCCTGAGCTC ATGGACGTGC ATGTCTTCTG CACAGACAGC ATCCAGGGGA CCCCCGTGGA GAGCGACGAA ATGCGCCCAT GCTGGTTCCA GCTGGATCAG ATCCCCTTCA AGGACATGTG GCCCGACGAC AGCTACTGGT TTCCACTCCT GCTTCAGAAG AAGAAATTCC ACGGGTACTT CAAGTTCCAG GGTCAGGACA CCATCCTGGA CTACACACTC CGCGAGGTGG ACACGGTCTA G

Additionnal Information

NUDT1, MTH1, ATGD0090-10 µg, ATGD0090-20 µg, ATGD0090-50 µg, ATGD0090-100 µg, ATGD0090-250 µg, ATGD0090-500 µg, ATGD0090-1 mg, ATGD0090-010, ATGD0090-020, ATGD0090-050, ATGD0090-100, ATGD0090-250, ATGD0090-500, ATGD0090-01M

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Enzymes & Proteases

Omim

600312

NCBI Accession Number

NP_945191.1

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_198953.1

DNA Size

471bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.