DNAJB8 cDNA

DNAJB8, also known as dnaJ homolog subfamily B member 8, is superior suppressors of aggregation and toxicity of disease-associated polyglutamine proteins. DNAJB8 is (de) acetylated at two conserved C-terminal lysines that are not involved in substrate binding, but do play a role in suppressing protein aggregation.

Product Specifications

Product Name Alternative

DJ6

Chromosomal Location

3q21.3

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGGCTAACT ACTACGAAGT GCTGGGCGTG CAGGCCAGCG CTTCCCCGGA GGACATCAAG AAAGCCTACC GCAAGCTGGC CCTTCGTTGG CACCCCGACA AGAACCCTGA CAATAAGGAG GAGGCGGAGA AGAAGTTCAA GCTGGTGTCT GAGGCCTATG AGGTTCTGTC TGACTCCAAG AAACGCTCCC TGTATGACCG TGCTGGCTGT GACAGCTGGC GGGCTGGTGG CGGGGCCAGC ACGCCCTACC ACAGCCCCTT CGACACCGGC TACACCTTCC GTAACCCTGA GGACATCTTC CGGGAGTTTT TCGGTGGCCT GGACCCTTTC TCCTTTGAGT TCTGGGACAG CCCATTCAAT AGTGACCGTG GTGGCCGGGG CCATGGCCTG AGGGGGGCCT TCTCGGCAGG CTTTGGAGAA TTTCCGGCCT TCATGGAGGC CTTCTCATCC TTCAACATGC TGGGCTGCAG CGGGGGCAGC CACACCACCT TCTCATCCAC CTCCTTCGGG GGCTCCAGTT CTGGCAGCTC GGGGTTCAAG TCGGTGATGT CGTCCACCGA GATGATCAAT GGCCACAAGG TCACCACCAA GCGCATCGTG GAGAACGGGC AGGAGCGCGT GGAGGTGGAG GAAGACGGGC AGCTCAAGTC GGTGACTGTG AACGGCAAGG AGCAGCTCAA ATGGATGGAC AGCAAGTAG

Additionnal Information

DNAJB8, DJ6, DNAJB8, ATGD0086-10 µg, ATGD0086-20 µg, ATGD0086-50 µg, ATGD0086-100 µg, ATGD0086-250 µg, ATGD0086-500 µg, ATGD0086-1 mg, ATGD0086-10, ATGD0086-20, ATGD0086-50, ATGD0086-100, ATGD0086-250, ATGD0086-500, ATGD0086-1

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Heat Shock Proteins

Omim

611337

NCBI Accession Number

NP_699161.1

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_153330.2

DNA Size

699bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.