ESRRA cDNA

ESRRA encoded by this gene is a nuclear receptor that is closely related to the estrogen receptor. ESRRA acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes. A processed pseudogene of ESRRA is located on chromosome 13q12. 1. Alternatively spliced transcript variants have been found for this gene.

Product Specifications

Product Name Alternative

ERR1, ERRa, ERRalpha, ESRL1, NR3B1, Steroid hormone receptor ERR1, Estrogen-related receptor alpha (ERR-alpha)

Chromosomal Location

11q13

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGTCCAGCC AGGTGGTGGG CATTGAGCCT CTCTACATCA AGGCAGAGCC GGCCAGCCCT GACAGTCCAA AGGGTTCCTC GGAGACAGAG ACCGAGCCTC CTGTGGCCCT GGCCCCTGGT CCAGCTCCCA CTCGCTGCCT CCCAGGCCAC AAGGAAGAGG AGGATGGGGA GGGGGCTGGG CCTGGCGAGC AGGGCGGTGG GAAGCTGGTG CTCAGCTCCC TGCCCAAGCG CCTCTGCCTG GTCTGTGGGG ACGTGGCCTC CGGCTACCAC TATGGTGTGG CATCCTGTGA GGCCTGCAAA GCCTTCTTCA AGAGGACCAT CCAGGGGAGC ATCGAGTACA GCTGTCCGGC CTCCAACGAG TGTGAGATCA CCAAGCGGAG ACGCAAGGCC TGCCAGGCCT GCCGCTTCAC CAAGTGCCTG CGGGTGGGCA TGCTCAAGGA GGGAGTGCGC CTGGACCGCG TCCGGGGTGG GCGGCAGAAG TACAAGCGGC GGCCGGAGGT GGACCCACTG CCCTTCCCGG GCCCCTTCCC TGCTGGGCCC CTGGCAGTCG CTGGAGGCCC CCGGAAGACA GCAGCCCCAG TGAATGCACT GGTGTCTCAT CTGCTGGTGG TTGAGCCTGA GAAGCTCTAT GCCATGCCTG ACCCCGCAGG CCCTGATGGG CACCTCCCAG CCGTGGCTAC CCTCTGTGAC CTCTTTGACC GAGAGATTGT GGTCACCATC AGCTGGGCCA AGAGCATCCC AGGCTTCTCA TCGCTGTCGC TGTCTGACCA GATGTCAGTA CTGCAGAGCG TGTGGATGGA GGTGCTGGTG CTGGGTGTGG CCCAGCGCTC ACTGCCACTG CAGGATGAGC TGGCCTTCGC TGAGGACTTA GTCCTGGATG AAGAGGGGGC ACGGGCAGCT GGCCTGGGGG AACTGGGGGC TGCCCTGCTG CAACTAGTGC GGCGGCTGCA GGCCCTGCGG CTGGAGCGAG AGGAGTATGT TCTACTAAAG GCCTTGGCCC TTGCCAATTC AGACTCTGTG CACATCGAAG ATGCCGAGGC TGTGGAGCAG CTGCGAGAAG CTCTGCACGA GGCCCTGCTG GAGTATGAAG CCGGCCGGGC TGGCCCCGGA GGGGGTGCTG AGCGGCGGCG GGCGGGCAGG CTGCTGCTCA CGCTACCGCT CCTCCGCCAG ACAGCGGGCA AAGTGCTGGC CCATTTCTAT GGGGTGAAGC TGGAGGGCAA GGTGCCCATG CACAAGCTGT TCTTGGAGAT GCTCGAGGCC ATGATGGACT GA

Additionnal Information

ESRRA, ERR1, ERRa, ERRalpha, ESRL1, NR3B1, ESRRA, ATGD0075-10 µg, ATGD0075-20 µg, ATGD0075-50 µg, ATGD0075-100 µg, ATGD0075-250 µg, ATGD0075-500 µg, ATGD0075-1 mg, ATGD0075-10, ATGD0075-20, ATGD0075-50, ATGD0075-100, ATGD0075-250, ATGD0075-500, ATGD0075-1

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Cancer

Omim

601998

NCBI Accession Number

NP_004442.3

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_004451.4

DNA Size

1272bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted BamH I to Hind III. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.