CBY1 cDNA

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. CBY1 encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene.

Product Specifications

Product Name Alternative

Arb1, C22orf2, CBY, HS508I15A, PGEA1, PIGEA-14, PIGEA14

Chromosomal Location

22q12

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGCCTTTCT TTGGGAATAC GTTCAGTCCG AAGAAGACAC CTCCTCGGAA GTCGGCATCT CTCTCCAACC TGCATTCTTT GGATCGATCA ACCCGGGAGG TGGAGCTGGG CTTGGAATAC GGATCCCCGA CTATGAACCT GGCAGGGCAA AGCCTGAAGT TTGAAAATGG CCAGTGGATA GCAGAGACAG GGGTTAGTGG CGGTGTGGAC CGGAGGGAGG TTCAGCGCCT TCGCAGGCGG AACCAGCAGT TGGAGGAAGA GAACAATCTC TTGCGGCTGA AAGTGGACAT CTTATTAGAC ATGCTTTCAG AGTCCACTGC TGAATCCCAC TTAATGGAGA AGGAACTGGA TGAACTGAGG ATCAGCCGGA AGAGAAAATG A

Additionnal Information

CBY1, arb1, C22orf2, CBY, HS508I15A, PGEA1, PIGEA-14, PIGEA14, CBY1, ATGD0074-10 µg, ATGD0074-20 µg, ATGD0074-50 µg, ATGD0074-100 µg, ATGD0074-250 µg, ATGD0074-500 µg, ATGD0074-1 mg, ATGD0074-10, ATGD0074-20, ATGD0074-50, ATGD0074-100, ATGD0074-250, ATGD0074-500, ATGD0074-1

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Epigenetics and Nuclear Signaling

Omim

607757

NCBI Accession Number

NP_056188.1

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_015373.3

DNA Size

381bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted Nde I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.