GMFB cDNA

GMFB, also known as GMF, belongs to the GMF subfamily of the larger actin-binding protein ADF family. This protein, which is phosphorylated following phorbol ester stimulation, is important for the nervous system. It causes brain cell differentiation, stimulates neural regeneration and inhibits tumor cell proliferation. Overexpression of GMFB in astrocytes has been shown to enhance brain-derived neurotrohic factor (BDNF) production. GMFB expression is increased by exercise, and the protein is crucial for exercise-induction of BDNF.

Product Specifications

Product Name Alternative

GMF

Chromosomal Location

14q22.2

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGAGTGAGT CTTTGGTTGT TTGTGATGTT GCCGAAGATT TAGTGGAAAA GCTGAGAAAG TTTCGTTTTC GCAAAGAAAC GAACAACGCT GCTATTATAA TGAAGATTGA CAAGGATAAA CGCCTGGTGG TACTGGATGA GGAGCTTGAG GGCATTTCAC CAGATGAACT TAAAGATGAA CTACCTGAAC GACAACCTCG CTTCATTGTG TATAGTTATA AATATCAACA TGATGATGGA AGAGTTTCAT ATCCTCTGTG CTTTATTTTC TCCAGTCCTG TTGGATGTAA GCCTGAACAA CAGATGATGT ATGCTGGAAG TAAGAATAAG CTAGTCCAGA CAGCTGAACT AACCAAGGTA TTTGAAATAA GAAATACCGA AGACCTAACT GAAGAATGGT TACGTGAGAA ACTTGGATTT TTTCACTAA

Additionnal Information

GMFB, GMF, GMFB, ATGD0058-10 µg, ATGD0058-20 µg, ATGD0058-50 µg, ATGD0058-100 µg, ATGD0058-250 µg, ATGD0058-500 µg, ATGD0058-1 mg, ATGD0058-10, ATGD0058-20, ATGD0058-50, ATGD0058-100, ATGD0058-250, ATGD0058-500, ATGD0058-1

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Neuroscience

Omim

601713

NCBI Accession Number

NP_004115.1

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_004124.2

DNA Size

429bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.