MSC cDNA

This gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway.

Product Specifications

Product Name Alternative

ABF-1, ABF1, bHLHa22, MYOR

Chromosomal Location

8q21

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGTCCACGG GCTCGGTGAG TGATCCGGAG GAGATGGAGC TTCGGGGGCT GCAGCGGGAG TACCCGGTCC CCGCCTCCAA GAGGCCGCCC CTCCGCGGCG TAGAGCGCAG CTACGCCTCG CCCAGTGACA ACTCGTCGGC AGAGGAGGAG GACCCCGACG GCGAGGAGGA GCGCTGCGCT CTGGGCACAG CCGGCAGCGC GGAAGGCTGC AAGAGGAAGC GGCCCCGTGT GGCTGGGGGC GGCGGCGCAG GTGGTAGCGC GGGCGGTGGT GGCAAGAAGC CCCTCCCGGC CAAGGGCTCA GCCGCAGAGT GCAAGCAGTC GCAGCGGAAC GCGGCCAACG CCCGTGAGCG TGCCCGGATG CGCGTGCTGA GCAAAGCCTT CTCCAGGCTC AAGACCAGCC TGCCCTGGGT GCCCCCCGAC ACTAAGCTCT CCAAGCTGGA CACGCTCCGG CTGGCTTCCA GTTACATCGC TCACCTGCGG CAGCTGTTGC AGGAGGACCG CTATGAGAAC GGCTACGTGC ACCCAGTGAA CCTGACATGG CCATTCGTGG TCTCGGGAAG ACCGGACTCT GACACCAAAG AAGTTTCCGC AGCCAACAGA CTATGTGGAA CCACCGCTTA A

Additionnal Information

MSC, ABF-1, ABF1, bHLHa22, MYOR, MSC, ATGD0053-10 µg, ATGD0053-20 µg, ATGD0053-50 µg, ATGD0053-100 µg, ATGD0053-250 µg, ATGD0053-500 µg, ATGD0053-1 mg, ATGD0053-10, ATGD0053-20, ATGD0053-50, ATGD0053-100, ATGD0053-250, ATGD0053-500, ATGD0053-1

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Epigenetics and Nuclear Signaling

Omim

603628

NCBI Accession Number

NP_005089.2

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_005098.3

DNA Size

621bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.