SEPSECS cDNA

SEPSECS, also known as SLA/LP autoantigen, catalyzes the final step of sec synthesis by converting O-phosphoseryl-tRNA (sec) to selenocysteinyl-tRNA (sec) using selenophosphate as the selenium donor. Also, this protein is considered a specific marker of autoimmune hepatitis.

Product Specifications

Product Name Alternative

LP, PCH2D, SLA, SLA/LP

Chromosomal Location

4p15.2

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGAACCGCG AGAGCTTCGC GGCGGGAGAG CGGCTGGTGT CGCCGGCTTA CGTGCGGCAG GGCTGTGAGG CCCGCCGCTC GCATGAGCAC CTCATACGGC TGCTTCTGGA GAAGGGCAAG TGTCCAGAGA ATGGCTGGGA TGAAAGTACA CTTGAACTCT TTTTACATGA ACTTGCAATC ATGGACAGCA ACAATTTCTT AGGCAATTGT GGTGTGGGAG AAAGGGAAGG GAGAGTGGCA TCCGCACTGG TTGCTCGTCG TCATTACAGG TTCATTCATG GCATTGGACG ATCCGGTGAT ATTTCTGCTG TGCAACCAAA AGCTGCAGGC TCTAGCCTTT TGAACAAAAT TACCAATTCT TTGGTCCTGG ACATTATAAA GCTGGCTGGT GTCCATACAG TAGCCAACTG CTTTGTAGTT CCTATGGCAA CTGGTATGAG TCTAACTCTG TGTTTCTTAA CATTACGACA CAAAAGACCA AAGGCAAAGT ATATTATATG GCCACGAATA GACCAGAAGT CCTGCTTTAA ATCCATGATC ACTGCAGGTT TTGAGCCTGT GGTGATAGAA AATGTTTTGG AAGGTGACGA GCTGCGTACA GACCTGAAAG CAGTGGAGGC TAAAGTCCAG GAACTTGGGC CTGATTGCAT TCTGTGTATT CATTCTACTA CATCCTGTTT TGCTCCAAGG GTGCCTGATA GATTAGAAGA ACTGGCTGTG ATTTGTGCTA ATTATGACAT TCCACATATA GTTAATAATG CTTATGGAGT GCAGTCTTCA AAGTGTATGC ATCTCATTCA GCAGGGGGCT CGAGTTGGTA GAATAGATGC TTTTGTTCAG AGCTTGGACA AAAATTTTAT GGTTCCAGTA GGTGGTGCTA TAATTGCTGG CTTTAATGAT TCATTCATTC AGGAAATCAG CAAGATGTAT CCAGGAAGAG CTTCAGCTTC ACCTTCTTTA GATGTCCTTA TTACTTTATT GTCACTTGGA TCAAATGGCT ATAAGAAGCT ACTAAAAGAA AGAAAGGAAA TGTTTTCATA TTTGTCCAAC CAAATAAAGA AGTTGTCAGA AGCCTACAAT GAAAGACTGT TGCATACACC TCACAATCCC ATATCTTTAG CTATGACACT TAAAACACTA GATGAACACC GTGACAAAGC TGTCACTCAG CTTGGCTCGA TGCTTTTTAC CAGACAGGTT TCTGGAGCCA GGGTTGTGCC TCTTGGGTCC ATGCAAACTG TGAGTGGCTA TACTTTCAGA GGCTTTATGT CACATACAAA TAATTACCCT TGTGCTTACC TCAATGCTGC ATCAGCCATC GGAATGAAGA TGCAGGATGT GGACCTGTTC ATAAAGAGAC TTGACAGGTG TTTAAAGGCA GTAAGAAAAG AACGAAGTAA AGAGAGTGAT GACAATTATG ACAAAACTGA AGATGTGGAT ATTGAAGAAA TGGCTTTAAA ACTAGATAAT GTACTTCTTG ACACATACCA GGATGCTTCT TCATGA

Additionnal Information

SEPSECS, LP, PCH2D, SLA, SLA/LP, SEPSECS, ATGD0048-10 µg, ATGD0048-20 µg, ATGD0048-50 µg, ATGD0048-100 µg, ATGD0048-250 µg, ATGD0048-500 µg, ATGD0048-1 mg, ATGD0048-10, ATGD0048-20, ATGD0048-50, ATGD0048-100, ATGD0048-250, ATGD0048-500, ATGD0048-1

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Enzymes & Proteases

Omim

613009

NCBI Accession Number

NP_058651.3

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_016955.3

DNA Size

1506bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted BamH I to Hind III. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.