UBE2N cDNA

UBE2N, also known as uBC13, is a member of the E2 ubiquitin-conjugating enzyme family. It catalyzes the ATP-dependent synthesis of non-canonical polyubiquitin chains, a process that does not lead to proteasomal degradation. It mediates the transcription of several target genes and is thought to play a role in cell cycle progression; cellular differentiation and DNA repair mechanisms that ensure cell survival after DNA damage.

Product Specifications

Product Name Alternative

Ubiquitin-conjugating enzyme E2N, UBC13, UbcH-ben

Chromosomal Location

12q22

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGGCCGGGC TGCCCCGCAG GATCATCAAG GAAACCCAGC GTTTGCTGGC AGAACCAGTT CCTGGCATCA AAGCCGAACC AGATGAGAGC AACGCCCGTT ATTTTCATGT GGTCATTGCT GGCCCTCAGG ATTCCCCCTT TGAGGGAGGG ACTTTTAAAC TTGAACTATT CCTTCCAGAA GAATACCCAA TGGCAGCCCC TAAAGTACGT TTCATGACCA AAATTTATCA TCCTAATGTA GACAAGTTGG GAAGAATATG TTTAGATATT TTGAAAGATA AGTGGTCCCC AGCACTGCAG ATCCGCACAG TTCTGCTATC GATCCAGGCC TTGTTAAGTG CTCCCAATCC AGATGATCCA TTAGCAAATG ATGTAGCGGA GCAGTGGAAG ACCAACGAAG CCCAAGCCAT AGAAACAGCT AGAGCATGGA CTAGGCTATA TGCCATGAAT AATATTTAA

Additionnal Information

UBE2N, HEL-S-71, UBC13, UbcH-ben, UbcH13, UBCHBEN, UBE2N, ATGD0044-10 µg, ATGD0044-20 µg, ATGD0044-50 µg, ATGD0044-100 µg, ATGD0044-250 µg, ATGD0044-500 µg, ATGD0044-1 mg, ATGD0044-10, ATGD0044-20, ATGD0044-50, ATGD0044-100, ATGD0044-250, ATGD0044-500, ATGD0044-1

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Ubiquitination

Omim

603679

NCBI Accession Number

NP_003339.1

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_003348.3

DNA Size

459bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.