AES cDNA

Amino-terminal enhancer of split, also known AES, belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. This protein is expressed predominately in fetal brain, liver, lung, heart and kidney and in adult muscle. In addition, AES can repress NFkB-regulated gene expression and is thought to play an important role in initiating and maintaining cell differentiation events.

Product Specifications

Product Name Alternative

AES-1, AES-2, ESP1, GRG, Grg-5, GRG5, TLE5

Chromosomal Location

19p13.3

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGATGTTTC CACAAAGCAG GCATTCGGGC TCCTCGCACC TACCCCAGCA ACTCAAATTC ACCACCTCGG ACTCCTGCGA CCGCATCAAA GACGAATTTC AGCTACTGCA AGCTCAGTAC CACAGCCTCA AGCTCGAATG TGACAAGTTG GCCAGTGAGA AGTCAGAGAT GCAGCGTCAC TATGTGATGT ACTACGAGAT GTCCTACGGC TTGAACATCG AGATGCACAA ACAGGCTGAG ATCGTCAAAA GGCTGAACGG GATTTGTGCC CAGGTCCTGC CCTACCTCTC CCAAGAGCAC CAGCAGCAGG TCTTGGGAGC CATTGAGAGG GCCAAGCAGG TCACCGCTCC CGAGCTGAAC TCTATCATCC GACAGCAGCT CCAAGCCCAC CAGCTGTCCC AGCTGCAGGC CCTGGCCCTG CCCTTGACCC CACTACCCGT GGGGCTGCAG CCGCCTTCGC TGCCGGCGGT CAGCGCAGGC ACCGGCCTCC TCTCGCTGTC CGCGCTGGGT TCCCAGGCCC ACCTCTCCAA GGAAGACAAG AACGGGCACG ATGGTGACAC CCACCAGGAG GATGATGGCG AGAAGTCGGA TTAG

Additionnal Information

AES, AES-1, AES-2, ESP1, GRG, Grg-5, GRG5, TLE5, AES, ATGD0043-10 µg, ATGD0043-20 µg, ATGD0043-50 µg, ATGD0043-100 µg, ATGD0043-250 µg, ATGD0043-500 µg, ATGD0043-1 mg, ATGD0043-10, ATGD0043-20, ATGD0043-50, ATGD0043-100, ATGD0043-250, ATGD0043-500, ATGD0043-1

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Signal Transduction

Omim

600188

NCBI Accession Number

NP_001121.2

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_001130.5

DNA Size

594bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.