DR1 cDNA

DR1, also known as NC2-beta, is a TBP (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. By selectively repressing polymerases II and III, DR1 may shift the physiological balance of transcriptional output in favor of polymerase I.

Product Specifications

Product Name Alternative

NC2, NC2-BETA

Chromosomal Location

1p22.1

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGGCTTCCT CGTCTGGCAA CGATGATGAT CTCACTATCC CCAGAGCTGC TATCAATAAA ATGATCAAAG AGACTCTTCC TAATGTCCGG GTGGCCAACG ATGCTCGAGA GCTGGTGGTG AACTGCTGCA CTGAATTCAT TCACCTTATA TCTTCTGAAG CCAATGAGAT TTGTAACAAA TCGGAAAAGA AGACCATCTC ACCAGAGCAT GTCATACAAG CACTAGAAAG TTTGGGATTT GGCTCTTACA TCAGTGAAGT AAAAGAAGTC TTGCAAGAGT GTAAAACAGT AGCATTAAAA AGAAGAAAGG CCAGTTCTCG TTTGGAAAAC CTTGGCATTC CTGAAGAAGA GTTATTGAGA CAGCAACAAG AATTATTTGC AAAAGCTAGA CAGCAACAAG CAGAATTGGC CCAACAGGAA TGGCTTCAAA TGCAGCAAGC TGCCCAACAA GCCCAGCTTG CTGCTGCCTC AGCCAGTGCA TCTAATCAGG CGGGATCTTC TCAGGATGAA GAAGATGATG ATGATATCTG A

Additionnal Information

DR1, NC2, NC2-BETA, DR1, ATGD0030-10 µg, ATGD0030-20 µg, ATGD0030-50 µg, ATGD0030-100 µg, ATGD0030-250 µg, ATGD0030-500 µg, ATGD0030-1 mg, ATGD0030-10, ATGD0030-20, ATGD0030-50, ATGD0030-100, ATGD0030-250, ATGD0030-500, ATGD0030-1

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Epigenomics (Transcription & Translation)

Omim

601482

NCBI Accession Number

NP_001929.1

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_001938.2

DNA Size

531bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted Nde I to BamH I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.