PHB2 cDNA

PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases by similarity. This protein functions as an estrogen receptor (ER) -selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging

Product Specifications

Product Name Alternative

Prohibitin 2, Bap37, p22, B cell receptor associated protein 37, BAP, BCAP37, PNAS-141, REA

Chromosomal Location

12p13

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGGCCCAGA ACTTGAAGGA CTTGGCGGGA CGGCTGCCCG CCGGGCCCCG GGGCATGGGC ACGGCCCTGA AGCTGTTGCT GGGGGCCGGC GCCGTGGCCT ACGGTGTGCG CGAATCTGTG TTCACCGTGG AAGGCGGGCA CAGAGCCATC TTCTTCAATC GGATCGGTGG AGTGCAGCAG GACACTATCC TGGCCGAGGG CCTTCACTTC AGGATCCCTT GGTTCCAGTA CCCCATTATC TATGACATTC GGGCCAGACC TCGAAAAATC TCCTCCCCTA CAGGCTCCAA AGACCTACAG ATGGTGAATA TCTCCCTGCG AGTGTTGTCT CGACCCAATG CTCAGGAGCT TCCTAGCATG TACCAGCGCC TAGGGCTGGA CTACGAGGAA CGAGTGTTGC CGTCCATTGT CAACGAGGTG CTCAAGAGTG TGGTGGCCAA GTTCAATGCC TCACAGCTGA TCACCCAGCG GGCCCAGGTA TCCCTGTTGA TCCGCCGGGA GCTGACAGAG AGGGCCAAGG ACTTCAGCCT CATCCTGGAT GATGTGGCCA TCACAGAGCT GAGCTTTAGC CGAGAGTACA CAGCTGCTGT AGAAGCCAAA CAAGTGGCCC AGCAGGAGGC CCAGCGGGCC CAATTCTTGG TAGAAAAAGC AAAGCAGGAA CAGCGGCAGA AAATTGTGCA GGCCGAGGGT GAGGCCGAGG CTGCCAAGAT GCTTGGAGAA GCACTGAGCA AGAACCCTGG CTACATCAAA CTTCGCAAGA TTCGAGCAGC CCAGAATATC TCCAAGACGA TCGCCACATC ACAGAATCGT ATCTATCTCA CAGCTGACAA CCTTGTGCTG AACCTACAGG ATGAAAGTTT CACCAGGGGA AGTGACAGCC TCATCAAGGG TAAGAAATGA

Additionnal Information

B cell receptor associated protein 37, BAP, BAP 37, BAP37, BCAP 37, BCAP37, p22, PHB2, PNAS 141, PNAS141, PNAS-141, Prohibitin 2, Prohibitin2, REA, ATGD0027-10 µg, ATGD0027-20 µg, ATGD0027-50 µg, ATGD0027-100 µg, ATGD0027-250 µg, ATGD0027-500 µg, ATGD0027-1 mg, ATGD0027-010, ATGD0027-020, ATGD0027-050, ATGD0027-100, ATGD0027-250, ATGD0027-500, ATGD0027-01M

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Signal Transduction

Omim

610704

NCBI Accession Number

NP_001138303.1

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_001144831.1

DNA Size

900bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted Nde I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.