MAP2K2 cDNA

MAP2K2, also known as MEK2, belongs to the STE grouping of kinases. Both MEK2 and the related MEK1 are dualspecificity kinases, phosphorylating and activating the mitogen-activated protein kinases ERK1 and ERK2 at T and Y positions within the phosphoacceptor sequence T-E-Y. MAP2K2 is activated by a wide variety of growth factors and cytokines and also by membrane depolarization and calcium influx.

Product Specifications

Product Name Alternative

Mitogen-activated protein kinase kinase 2, MAP kinase kinase 2, MAPKK2, MAPK/ERK kinase 2, MEK2, MKK2, PRKMK2, ERK activator kinase 2

Chromosomal Location

19q13.3

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGCTGGCCC GGAGGAAGCC GGTGCTGCCG GCGCTCACCA TCAACCCTAC CATCGCCGAG GGCCCATCCC CTACCAGCGA GGGCGCCTCC GAGGCAAACC TGGTGGACCT GCAGAAGAAG CTGGAGGAGC TGGAACTTGA CGAGCAGCAG AAGAAGCGGC TGGAAGCCTT TCTCACCCAG AAAGCCAAGG TCGGCGAACT CAAAGACGAT GACTTCGAAA GGATCTCAGA GCTGGGCGCG GGCAACGGCG GGGTGGTCAC CAAAGTCCAG CACAGACCCT CGGGCCTCAT CATGGCCAGG AAGCTGATCC ACCTTGAGAT CAAGCCGGCC ATCCGGAACC AGATCATCCG CGAGCTGCAG GTCCTGCACG AATGCAACTC GCCGTACATC GTGGGCTTCT ACGGGGCCTT CTACAGTGAC GGGGAGATCA GCATTTGCAT GGAACACATG GACGGCGGCT CCCTGGACCA GGTGCTGAAA GAGGCCAAGA GGATTCCCGA GGAGATCCTG GGGAAAGTCA GCATCGCGGT TCTCCGGGGC TTGGCGTACC TCCGAGAGAA GCACCAGATC ATGCACCGAG ATGTGAAGCC CTCCAACATC CTCGTGAACT CTAGAGGGGA GATCAAGCTG TGTGACTTCG GGGTGAGCGG CCAGCTCATC GACTCCATGG CCAACTCCTT CGTGGGCACG CGCTCCTACA TGGCTCCGGA GCGGTTGCAG GGCACACATT ACTCGGTGCA GTCGGACATC TGGAGCATGG GCCTGTCCCT GGTGGAGCTG GCCGTCGGAA GGTACCCCAT CCCCCCGCCC GACGCCAAAG AGCTGGAGGC CATCTTTGGC CGGCCCGTGG TCGACGGGGA AGAAGGAGAG CCTCACAGCA TCTCGCCTCG GCCGAGGCCC CCCGGGCGCC CCGTCAGCGG TCACGGGATG GATAGCCGGC CTGCCATGGC CATCTTTGAA CTCCTGGACT ATATTGTGAA CGAGCCACCT CCTAAGCTGC CCAACGGTGT GTTCACCCCC GACTTCCAGG AGTTTGTCAA TAAATGCCTC ATCAAGAACC CAGCGGAGCG GGCGGACCTG AAGATGCTCA CAAACCACAC CTTCATCAAG CGGTCCGAGG TGGAAGAAGT GGATTTTGCC GGCTGGTTGT GTAAAACCCT GCGGCTGAAC CAGCCCGGCA CACCCACGCG CACCGCCGTG TGA

Additionnal Information

PRKMK-2, PRKMK2, PRKMK 2, MKK-2, MKK2, MKK 2, Mitogen-activated protein kinase kinase 2, Mitogen activated protein kinase kinase 2, MEK-2, MEK2, MEK 2, MAPKK-2, MAPKK2, MAPKK 2, MAPK/ERK kinase 2, MAP2K2, MAP kinase kinase 2, ERK activator kinase 2, Dual specificity mitogen-activated protein kinase kinase 2, Dual specificity mitogen activated protein kinase kinase 2, CFC4, ATGD0016-10 µg, ATGD0016-20 µg, ATGD0016-50 µg, ATGD0016-100 µg, ATGD0016-250 µg, ATGD0016-500 µg, ATGD0016-1 mg, ATGD0016-010, ATGD0016-020, ATGD0016-050, ATGD0016-100, ATGD0016-250, ATGD0016-500, ATGD0016-01M

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Cancer

Omim

601263

NCBI Accession Number

NP_109587.1

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_030662.3

DNA Size

1203bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.