FKBP3 cDNA

FK506 binding protein 3 (FKBP3), also known as FKBP25, is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBP3 associates with transcriptional repressor protein YY1 and histone deaceltylases, HDAC1 and HDAC2. Also, FKBP3 may contain several casein kinase II phosphorylation sites, which are believed to be important for cell growth regulation. It is localized in the nucleus and is expressed in the brain, testis, ovary, and spleen.

Product Specifications

Product Name Alternative

FKBP-25, FKBP-3, FKBP25, PPIase

Chromosomal Location

14q21.2

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGGCGGCGG CCGTTCCACA GCGGGCGTGG ACCGTGGAGC AGCTGCGCAG TGAGCAGCTG CCCAAGAAGG ACATTATCAA GTTTCTGCAG GAACACGGTT CAGATTCGTT TCTTGCAGAA CATAAATTAT TAGGAAACAT TAAAAATGTG GCCAAGACAG CTAACAAGGA CCACTTGGTT ACAGCCTATA ACCATCTTTT TGAAACTAAG CGTTTTAAGG GTACTGAAAG TATAAGTAAA GTGTCTGAGC AAGTAAAAAA TGTGAAGCTT AATGAAGATA AACCCAAAGA AACCAAGTCT GAAGAGACCC TGGATGAGGG TCCACCAAAA TATACTAAAT CTGTTCTGAA AAAGGGAGAT AAAACCAACT TTCCCAAAAA GGGAGATGTT GTTCACTGCT GGTATACAGG AACACTACAA GATGGGACTG TTTTTGATAC TAATATTCAA ACAAGTGCAA AGAAGAAGAA AAATGCCAAG CCTTTAAGTT TTAAGGTCGG AGTAGGCAAA GTTATCAGAG GATGGGATGA AGCTCTCTTG ACTATGAGTA AAGGAGAAAA GGCTCGACTG GAGATTGAAC CAGAATGGGC TTACGGAAAG AAAGGACAGC CTGATGCCAA AATTCCACCA AATGCAAAAC TCACTTTTGA AGTGGAATTA GTGGATATTG ATTGA

Additionnal Information

FKBP3, FKBP-25, FKBP-3, FKBP25, PPIase, FKBP3, ATGD0010-10 µg, ATGD0010-20 µg, ATGD0010-50 µg, ATGD0010-100 µg, ATGD0010-250 µg, ATGD0010-500 µg, ATGD0010-1 mg, ATGD0010-10, ATGD0010-20, ATGD0010-50, ATGD0010-100, ATGD0010-250, ATGD0010-500, ATGD0010-1

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Heat Shock Proteins

Omim

186947

NCBI Accession Number

NP_002004.1

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_002013.3

DNA Size

675bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.