GLRX3 cDNA

Glutaredoxin (GRX), also known as thioltransferase, is member of the thiol-disulfide oxidoreductase family. Glutraredoxin catalyzes the reversible reduction of protein-glutathionyl mixed disulfides to free sulfhydryl groups though a monothiol mechanism. Glutaredoxin-3 (Grx3/PICOT) is an essential protein involved in the regulation of signal transduction, for instance during immune cell activation and development of cardiac hypertrophy, presumably in response to redox signals. And it has been shown to interact with PRKCQ

Product Specifications

Product Name Alternative

Glutaredoxin-3, GRX3, PKC-interacting cousin of thioredoxin, PKC-theta-interacting protein, PKCq-interacting protein, Thioredoxin-like protein 2, Glutaredoxin 4, GLRX4, GRX4, PICOT, TXNL2, HUSSY-22, bA500G10.4

Chromosomal Location

10q26

Antigen Species

Human

Vector Type

PATGen (puc19-derived cloning vector)

Sequence

ATGGCGGCGG GGGCGGCTGA GGCAGCTGTA GCGGCCGTGG AGGAGGTCGG CTCAGCCGGG CAGTTTGAGG AGCTGCTGCG CCTCAAAGCC AAGTCCCTCC TTGTGGTCCA TTTCTGGGCA CCATGGGCTC CACAGTGTGC ACAGATGAAC GAAGTTATGG CAGAGTTAGC TAAAGAACTC CCTCAAGTTT CATTTGTGAA GTTGGAAGCT GAAGGTGTTC CTGAAGTATC TGAAAAATAT GAAATTAGCT CTGTTCCCAC TTTTCTGTTT TTCAAGAATT CTCAGAAAAT CGACCGATTA GATGGTGCAC ATGCCCCAGA GTTGACCAAA AAAGTTCAGC GACATGCATC TAGTGGCTCC TTCCTACCCA GCGCTAATGA ACATCTTAAA GAAGATCTCA ACCTTCGCTT GAAGAAATTG ACTCATGCTG CCCCCTGCAT GCTGTTTATG AAAGGAACTC CTCAAGAACC ACGCTGTGGT TTCAGCAAGC AGATGGTGGA AATTCTTCAC AAACATAATA TTCAGTTTAG CAGTTTTGAT ATCTTCTCAG ATGAAGAGGT TCGACAGGGA CTCAAAGCCT ATTCCAGTTG GCCTACCTAT CCTCAGCTCT ATGTTTCTGG AGAGCTCATA GGAGGACTTG ATATAATTAA GGAGCTAGAA GCATCTGAAG AACTAGATAC AATTTGTCCC AAAGCTCCCA AATTAGAGGA AAGGCTCAAA GTGCTGACAA ATAAAGCTTC TGTGATGCTC TTTATGAAAG GAAACAAACA GGAAGCAAAA TGTGGATTCA GCAAACAAAT TCTGGAAATA CTAAATAGTA CTGGTGTTGA ATATGAAACA TTCGATATAT TGGAGGATGA AGAAGTTCGG CAAGGATTAA AAGCTTACTC AAATTGGCCA ACATACCCTC AGCTGTATGT GAAAGGGGAG CTGGTGGGAG GATTGGATAT TGTGAAGGAA CTGAAAGAAA ATGGTGAATT GCTGCCTATA CTGAGAGGAG AAAATTAA

Additionnal Information

TXNL2, TXNL 2, Thioredoxin-like2, Thioredoxin-like protein 2, Thioredoxin-like 2, Thioredoxin like 2, PKC-theta-interacting protein, PKCq-interacting protein, PKCq interacting protein, PKC-interacting cousin of thioredoxin, PKC theta interacting protein, PKC interacting cousin of thioredoxin, PICOT, HUSSY-22, GRX4, GRX3, Glutaredoxin-4, Glutaredoxin4, Glutaredoxin-3, Glutaredoxin3, Glutaredoxin 4, Glutaredoxin 3, GLRX4, GLRX3, bA500G10.4, ATGD0009-10 µg, ATGD0009-20 µg, ATGD0009-50 µg, ATGD0009-100 µg, ATGD0009-250 µg, ATGD0009-500 µg, ATGD0009-1 mg, ATGD0009-010, ATGD0009-020, ATGD0009-050, ATGD0009-100, ATGD0009-250, ATGD0009-500, ATGD0009-01M

Storage Conditions

Store the plasmid at -20C.

Formulation

Lyophilized

Scientific Category

Redox Proteins

Omim

612754

NCBI Accession Number

NP_006532.2

Species

Human

Preparation

1. Centrifuge at 7000rpm for 1 minute.; ;2. Carefully open the vial and add 100 µL of sterile water to dissolve the DNA.; ; Each tube contains approximately 10 µg of lyophilized plasmid.

RNA Reference

NM_006541.4

DNA Size

1008bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.