Human NKp30/NCR3 antibody
NCR3, also known as NKP30, is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene.
Product Specifications
Product Name Alternative
Natural cytotoxicity triggering receptor 3, 1C7, CD337, LY117, MALS, NKp30
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human NCR3 (19-138aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
AT38D9
Conjugation
Unconjugated
Applications
ELISA, WB
Purification Method
By protein-A affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
References & Citations
Venter J.C., et al. (2001) Science. 291:1304-1351.; ; Gerhard D.S., et al. (2004) Genome Res. 14:2121-2127.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
Scientific Category
Immunology
NCBI Accession Number
NP_001138939
Uniprot Accession Number
O14931
WB Description
Frequently Asked Questions
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