Human MP1/LAMTOR3 antibody
MAPKSP1 (Mitogen-activated protein kinase scaffold protein 1) is a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2.
Product Specifications
Product Name Alternative
Mitogen-activated protein kinase scaffold protein 1, MAP2K1IP1, MAPBP, MP1
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human MAPKSP1 (1-124aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
AT1F10
Conjugation
Unconjugated
Applications
ELISA, WB, ICC/IF
Purification Method
By protein-A affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
References & Citations
Wunderlich, et al. (2001) J. Cell Biol. (United States) 152 (4) : 765-76. ; ; Schaeffer HJ, et al. (1998) Science 281 (5383) : 1668-71.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
Scientific Category
Signal Transduction
NCBI Accession Number
NP_068805
Uniprot Accession Number
Q9UHA4
WB Description
IF Description
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