What is the catalog number for Human SSU72 antibody?

The catalog number for Human SSU72 antibody is ATGA0469-050.

What sizes are available for Human SSU72 antibody?

Human SSU72 antibody is available in the following size(s): 50 µL.

Is Human SSU72 antibody in stock?

Human SSU72 antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Human SSU72 antibody

SSU72 RNA polymerase II CTD phosphatase homolog, also known as SSU72, is a highly conserved homologue of yeast Ssu72, a CTD phosphatase and a component of the polyadenylation/ termination machinery. Existing as multiple alternatively spliced isoforms, SSU72 interacts with TFIIB, Rb and DNAM-1 and functions to catalyze the dephosphorylation of target proteins, possibly playing a role in RNA processing and termination via dephosphorylation of Pol II.

Product Specifications

Product Name Alternative

SSu72 RNA polymerase II CTD phosphatase homolog, HSPC182, PNAS-120

Host

Mouse

Antigen Species

Human

Reactivity

Human

Immunogen

Recombinant human SSU72 (1-194aa) purified from E. coli

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

AT66D10

Conjugation

Unconjugated

Applications

ELISA, WB

Purification Method

By protein-A affinity chromatography

Concentration

1 mg/mL (determined by BCA assay)

Additionnal Information

SSU72, ATGA0469-10 µg, ATGA0469-20 µg, ATGA0469-50 µg, ATGA0469-100 µg, ATGA0469-250 µg, ATGA0469-500 µg, ATGA0469-1 mg, ATGA0469-10, ATGA0469-20, ATGA0469-50, ATGA0469-100, ATGA0469-250, ATGA0469-500, ATGA0469-1

References & Citations

Dichtl B., et al. (2002) Mol Cell. 10: 1139-1150.; ; Krishnamurthy S., et al. (2004) Mol Cell. 14: 387-394.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Applications Notes

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Scientific Category

Epigenomics (Transcription & Translation)

NCBI Accession Number

NP_054907

Uniprot Accession Number

Q9NP77

WB Description

The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human SSU72 antibody (1:1000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.; ; Lane 1.: Jurkat cell lysate; ; Lane 2.: K562 cell lysate; ; Lane 3.: 293T cell lysate; ; Lane 4.: HepG2 cell lysate; ; Lane 5.: A549 cell lysate; ; Lane 6.: MCF-7 cell lysate; ; Lane 7.: SK-OV-3 cell lysate; ; Lane 8.: LnCap cell lysate; ; Lane 9.: HeLa cell lysate