What is the catalog number for Human TIP30/HTATIP2 antibody?

The catalog number for Human TIP30/HTATIP2 antibody is ATGA0444-050.

What sizes are available for Human TIP30/HTATIP2 antibody?

Human TIP30/HTATIP2 antibody is available in the following size(s): 50 µL.

Is Human TIP30/HTATIP2 antibody in stock?

Human TIP30/HTATIP2 antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Human TIP30/HTATIP2 antibody

HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II) . Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy.

Product Specifications

Product Name Alternative

Oxidoreductase HTATP2, CC3, TIP30, SDR44u1, Oxidoreductase HTATP2, HTATIP 2, HTATIP-2, CC-3, TIP 30, TIP-30

Host

Mouse

Antigen Species

Human

Reactivity

Human

Immunogen

Recombinant human HTATIP2 (1-242aa) purified from E. coli

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

AT5D6

Conjugation

Unconjugated

Applications

ELISA, WB, ICC/IF

Purification Method

By protein-A affinity chromatography

Concentration

1 mg/mL (determined by BCA assay)

Additionnal Information

TIP-30, TIP30, TIP 30, SDR44u1, Oxidoreductase HTATP2, HTATIP-2, HTATIP2, HTATIP 2, CC-3, CC3, CC 3, ATGA0444-10 µg, ATGA0444-20 µg, ATGA0444-50 µg, ATGA0444-100 µg, ATGA0444-250 µg, ATGA0444-500 µg, ATGA0444-1 mg, ATGA0444-010, ATGA0444-020, ATGA0444-050, ATGA0444-100, ATGA0444-250, ATGA0444-500, ATGA0444-01M

References & Citations

Shtivelman E., et al. (1997) Oncogene. 14 (18) : 2167-73. ; ; Xiao H., et al. (1998) Proc Natl Acad Sci u S A. 95 (5) : 2146-2151.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Applications Notes

The antibody has been tested by ELISA, Western blot analysis, Flow cytometry and ICC/IF to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Scientific Category

Apoptosis

NCBI Accession Number

AAH15358

Uniprot Accession Number

Q9BUP3

WB Description

The cell lysate (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human HTATIP2 antibody (1:1000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. ; ; Lane 1 : HeLa cell lysate

IF Description

ICC/IF analysis of HTATIP2 in A549 cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human HTATIP2 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green) . ICC/IF analysis of HTATIP2 in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human HTATIP2 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green) . {ATGA0444-IF2.jpg}