Human BAG2 antibody
BCL2-associated athanogene 2, also known as BAG2, is a member of the Bag family of proteins. BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain. BAG2 is a major component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex and acts to disrupt CHIP-mediated ubiquitylation.
Product Specifications
Product Name Alternative
BCL2-associated athanogene 2, BAG-2
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human BAG2 (1-211aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
AT29E9
Conjugation
Unconjugated
Applications
ELISA, WB, ICC/IF
Purification Method
By protein-A affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
References & Citations
Takayama S., et al. (1999) J Biol Chem. 274: 781-786.; ; Arndt V., et al. (2005) CHIP Mol Biol Cell. 16: 5891-5900.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
Scientific Category
Apoptosis
NCBI Accession Number
NP_004273
Uniprot Accession Number
O95816
WB Description
IF Description
Frequently Asked Questions
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