Human Calbindin 2/CALB2 antibody
CALB2 is an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers.
Product Specifications
Product Name Alternative
CR, Calretinin, CALB2, CAL2, CAB29, 29 kDa calbindin
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human CALB2 (1-271aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
AT5C5
Conjugation
Unconjugated
Applications
ELISA, WB, ICC/IF
Purification Method
By protein-A affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
References & Citations
Rogers JH., et al. (1987) J Cell Biol. 105 (3) : 1343-1353.; ; Dreher B., et al. (1996) J. Comp. Neurol. 376 (2) : 223-40.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
Scientific Category
Neuroscience
NCBI Accession Number
AAH15484
Uniprot Accession Number
P22676
WB Description
IF Description
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