What is the catalog number for Human VHR/DUSP3 antibody?

The catalog number for Human VHR/DUSP3 antibody is ATGA0374-050.

What sizes are available for Human VHR/DUSP3 antibody?

Human VHR/DUSP3 antibody is available in the following size(s): 50 µL.

Is Human VHR/DUSP3 antibody in stock?

Human VHR/DUSP3 antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Human VHR/DUSP3 antibody

DUSP3, also known as Dual specificity protein phosphatase 3, is inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.

Product Specifications

Product Name Alternative

Dual specificity protein phosphatase 3, VHR, Dual specificity protein phosphatase VHR, Vaccinia H1-related phosphatase, Vaccinia virus phosphatase VH1-related

Host

Mouse

Antigen Species

Human

Reactivity

Human

Immunogen

Recombinant human DUSP3 (1-185aa) purified from E. coli

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

AT9E6

Conjugation

Unconjugated

Applications

ELISA, WB

Purification Method

By protein-A affinity chromatography

Concentration

1 mg/mL (determined by BCA assay)

Additionnal Information

VHR, ATGA0374-10 µg, ATGA0374-20 µg, ATGA0374-50 µg, ATGA0374-100 µg, ATGA0374-250 µg, ATGA0374-500 µg, ATGA0374-1 mg, ATGA0374-10, ATGA0374-20, ATGA0374-50, ATGA0374-100, ATGA0374-250, ATGA0374-500, ATGA0374-1

References & Citations

Sun H. (1998) Mol Biol. 84: 307-318.; ; Folander K., et al. (1995) Genomics. 23 (1) : 295-296.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Applications Notes

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Scientific Category

Signal Transduction

NCBI Accession Number

NP_004081

Uniprot Accession Number

P51452

WB Description

The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human VHR antibody (1:3000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.; ; Lane 1.: HeLa cell lysate; ; Lane 2.: HepG2 cell lysate; ; Lane 3.: Jurkat cell lysate; ; Lane 4.: MCF7 cell lysate; ; Lane 5.: 293T cell lysate; ; Lane 6.: U87MG cell lysate; ; Lane 7.: K562 cell lysate