What is the catalog number for Human MFAP4 antibody?

The catalog number for Human MFAP4 antibody is ATGA0268-100.

What sizes are available for Human MFAP4 antibody?

Human MFAP4 antibody is available in the following size(s): 100 µL.

Is Human MFAP4 antibody in stock?

Human MFAP4 antibody is currently made to order / not held in immediate stock. Contact us for lead time.

Human MFAP4 antibody

Several microfibril associated proteins (MFAPs) have been cloned, including MFAP1, MFAP3 and MFAP4. The MFAP1 and MFAP3 genes are localized near the fibrillin genes FBN1 and FBN2, respectively. Mutations in FBN1 are linked to Marfan syndrome. Mutations in FBN2 have been linked to congenital contractural arachnodactyly. This suggests roles for MFAP1 and MFAP3 in heritable diseases affecting microfibrils. Deletion of MFAP4 was found in 30 of 31 patients with Smith-Magenis syndrome (SMS), a clinically recognizable multiple congenital anomaly/mental retardation syndrome. Also, MFAP4 play an important role in calcium-dependent cell adhesion or intercellular interactions. These structural features of MFAP4 suggest that it is an extracellular matrix protein involved in cell adhesion or intercellular interactions.

Product Specifications

Product Name Alternative

Microfibrillar-associated protein 4, microfibrillar-associated protein 4, Microfibril associated glycoprotein 4, Microfibril-associated glycoprotein 4

Host

Mouse

Antigen Species

Human

Reactivity

Human

Immunogen

Recombinant human MFAP4 (22-255aa) purified from E. coli

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

AT12D11

Conjugation

Unconjugated

Applications

ELISA, WB

Purification Method

By protein-A affinity chromatography

Concentration

1 mg/mL (determined by BCA assay)

Additionnal Information

MFAP4, ATGA0268-10 µg, ATGA0268-20 µg, ATGA0268-50 µg, ATGA0268-100 µg, ATGA0268-250 µg, ATGA0268-500 µg, ATGA0268-1 mg, ATGA0268-10, ATGA0268-20, ATGA0268-50, ATGA0268-100, ATGA0268-250, ATGA0268-500, ATGA0268-1

References & Citations

Zhao, Z., et al. (1995) Hum Mol Genet 4 (4) : 589-97.; ; Kasamatsu, S., et al. (2011) Sci Rep 1:164.

Storage Conditions

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Formulation

Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol

Applications Notes

The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.

Scientific Category

Signal Transduction

NCBI Accession Number

NP_002395

Uniprot Accession Number

P55083

WB Description

The tissue lysate of lung (30ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human MFAP4 antibody (1:1000) . Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.