Human SNTA1 antibody
SNTA1 (Syntrophin alpha 1) is 505 amino acid protein. SNTA1 is adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. It may link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. SNTA1 plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Defects of SNTA1 are the cause of long QT syndrome type 12 (LQT12) .
Product Specifications
Product Name Alternative
Syntrophin alpha 1, Syntrophin, alpha 1, dJ1187J4.5, LQT12, SNT1, TACIP1
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human SNTA1 (1-505aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
AT1E1
Conjugation
Unconjugated
Applications
ELISA, WB, ICC/IF
Purification Method
By protein-A affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
References & Citations
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
Scientific Category
Cytoskeleton
NCBI Accession Number
NP_003089
Uniprot Accession Number
Q13424
WB Description
IF Description
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