Human PIG3/TP53I3 antibody
TP53I3 participates in the generation of reactive oxygen species (ROS) . TP53I3 has low NADPH-dependent naphtoquinone reductase activity, with a preference for 1, 2-naphtoquinone over 1, 4-naphtoquinone. TP53I3 has low NADPH-dependent diamine reductase activity (in vitro) . TP53I3 is localized to the cytoplasm and induced in primary, non-transformed and transformed cell cultures after exposure to genotoxic agents. TP53I3 microsatellite polymorphism is associated with differential susceptibility to cancer.
Product Specifications
Product Name Alternative
Quinone oxidoreductase PIG3, NADPH:quinone reductase PIG3, Tumor protein p53-inducible protein 3, p53-induced gene 3 protein
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human TP53I3 (1-332aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
AT1C9
Conjugation
Unconjugated
Applications
ELISA, WB, ICC/IF
Purification Method
By protein-G affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
References & Citations
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
Scientific Category
Cancer
NCBI Accession Number
NP_671713
Uniprot Accession Number
Q53FA7
WB Description
IF Description
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