Human Aldo-keto reductase 7A3/AKR7A3 antibody
Aldo-keto reductase family 7, member A 3 (AKR7A3) is a member of the aldo/keto reductase superfamily involved in the detoxification and metabolism of a variety of exogenous aldehydes and ketones. The activity of AKR7A3 may detoxify the aflatoxin B1 (AFB1) dialdehyde, which reacts with proteins, and thereby inhibitis AFB1 induced toxicity. AKR7A3 is expressed in kidney, colon, pancreas, endometrium and adenocarcinoma.
Product Specifications
Product Name Alternative
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human AKR7A3 (1-331aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
AT2E11
Conjugation
Unconjugated
Applications
ELISA, WB
Purification Method
By protein-G affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
References & Citations
Chem Res Toxicol 2008, 21:1134-1142.; ; J. Biol. Chem. 267 (34) : 24841-7. ; ; Chem Res Toxicol 2008, 21:1134-1142.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
Scientific Category
Signal Transduction
NCBI Accession Number
AAH25709
Uniprot Accession Number
O95154
WB Description
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
MART-1 / Melan-A (M2-7C10), CF640R conjugate, 0.1mg/mL
CD81 / TAPA-1 (1.3.3.22), CF640R conjugate, 0.1mg/mL
Tyrosinase (T311), CF640R conjugate, 0.1mg/mL
CD50 / ICAM3 (CG106), CF740 conjugate, 0.1mg/mL
