Human Retinol Binding Protein 4/RBP4 antibody
Retinol binding protein 4 (RBP4) belongs to the lipocalin family and is the specific carrier for retinol in the blood. This protein was found to be expressed and secreted by adipose tissue, and was strongly associated with insulin resistance. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli.
Product Specifications
Product Name Alternative
Plasma retinol-binding protein, PRBP, RBP
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human RBP4 (19-201aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
AT2B4
Conjugation
Unconjugated
Applications
ELISA, WB, ICC/IF, FACS
Purification Method
By protein-G affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
References & Citations
Tan Bk, et al., (2007) J Clin Endocrinol Metab 92 (7) :2590-2597.; ; Yao-Borengasser A, et al., (2007) J Clin Endocrinol Metab 92 (7) :2430-2432.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
Scientific Category
Metabolism
NCBI Accession Number
NP_006735
Uniprot Accession Number
P02753
WB Description
FACS Description
IF Description
Frequently Asked Questions
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