Human CRABP2 antibody
The cellular retinoic acid-binding protein II (CRABP-II) is involved in the conversion of vitamin A into its intracellular active form retinoic acid, which regulate the genes responsible for lipid metabolism and adipocyte differentiation. CRABP2 gene is located on chromosome 1q21-23 and this region has been linked with related disorders such as familial combined hyperlipidemia (FCHL) and type 2 diabetes mellitus.
Product Specifications
Product Name Alternative
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human CRABP2 (1-138aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
AT2E11
Conjugation
Unconjugated
Applications
ELISA, WB, ICC/IF
Purification Method
By protein-G affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
References & Citations
Astrom, A., et al (1991) . J. Biol. Chem. 266 (26), 17662-17666.; ; Gupta, A., et al (2006) . Cancer Res. 66 (16), 8100-8108.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
Scientific Category
Epigenomics (Transcription & Translation)
NCBI Accession Number
NP_001869
Uniprot Accession Number
P29373
WB Description
IF Description
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