Human Carbonyl reductase 3/CBR3 antibody
Carbonyl reductase 3 (CBR3) is one of several monomeric NADPH-dependent oxidoreductases. This protein catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. It also contains three exons spanning 11. 2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. Some studies suggest that it mediates 9-cis-retinoic acid-induced cytostatis and is a potential prognostic marker for oral malignancy.
Product Specifications
Product Name Alternative
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human CBR3 (1-277aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
AT7E8
Conjugation
Unconjugated
Applications
ELISA, WB, ICC/IF
Purification Method
By protein-G affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
References & Citations
Ohkura-Hada S., et al. (2008) . Open Dent J. 2: 78-88. ; ; Miura T., et al. (2009) . Life Sci. 85 (7-8) : 303-8.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
Scientific Category
Metabolism
NCBI Accession Number
NP_001227
Uniprot Accession Number
O75828
WB Description
IF Description
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