Human KCTD15 antibody
KCTD15 (Potassium channel tetramerisation domain containing 15, also known as BTB/POZ domain-containing protein KCTD15) is protein that in humans is encoded by the KCTD15 gene. KCTD15 is expressed at high level in brain and hypothalamus. The potassium channel KCTD15 was identified as a genetic loci associated with higher than normal body mass index (BMI) in humans along with genes such as GNPDA2, MTCH2, FTO, and TMEM18. Single nucleotide polymorphisms (SNPs) in non-diabetic and diabetic patients showed that FTO was most strongly associated with obesity while MTCH2 and GNPDA2 were still significantly associated with higher than normal BMI levels.
Product Specifications
Product Name Alternative
BTB/POZ domain-containing protein KCTD15, MGC25497, MGC2628
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human KCTD15 (1-159aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
AT2B11
Conjugation
Unconjugated
Applications
ELISA, WB, ICC/IF, FACS
Purification Method
By protein-G affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
References & Citations
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
Scientific Category
Neuroscience
NCBI Accession Number
NP_076981
Uniprot Accession Number
Q96SI1
WB Description
FACS Description
IF Description
ICC/IF analysis of KCTD15 in HeLa cells. The cell was stained with ATGA0121 (1:100) . The secondary antibody (green) was used Alexa Fluor 488.
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