Human FABP4/A-FABP antibody
FABP4 (Fatty acid binding protein 4) is expressed in adipocytes and macrophages, and integrates inflammatory and metabolic responses. FABP4 is thought to regulate fatty acid uptake, release, and storage in adipocytes and participates in systemic glucose homeostasis and in macrophage responses in atherosclerosis. Blocking this protein either through genetic engineering or drugs has the possibility of treating heart disease, diabetes, asthma, obesity, and fatty liver disease.
Product Specifications
Product Name Alternative
Fatty acid binding protein 4, fatty acid binding protein 4 adipocyte, A-FABP, aP2
Host
Mouse
Antigen Species
Human
Reactivity
Human
Immunogen
Recombinant human FABP4 (1-132aa) purified from E. coli
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
3F4
Conjugation
Unconjugated
Applications
ELISA, WB, ICC/IF
Purification Method
By protein-G affinity chromatography
Concentration
1 mg/mL (determined by BCA assay)
Additionnal Information
References & Citations
Furuhashi M., et al., (2007) Nature. 21.447 (7147) :959-65.; ; Shum BO, et al., (2006) J Clin Invest. 116 (8) :2183-92.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Applications Notes
Scientific Category
Enzymes & Proteases
NCBI Accession Number
NP_001433
Uniprot Accession Number
P15090
WB Description
IF Description
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Centaurin alpha 1 (ADAP1) (NM_006869) Human Recombinant Protein