Enzalutamide carboxylic acid
Enzalutamide carboxylic acid (MDV3100 carboxylic acid) is an inactive metabolite of Enzalutamide (MDV3100) . Enzalutamide is an androgen receptor (AR) antagonist[1].
Product Specifications
CAS Number
[1242137-15-0]
Product Name Alternative
MDV3100 carboxylic acid
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/enzalutamide-carboxylic-acid.html
Concentration
10mM
Purity
98.11
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(O)C1=CC=C(N(C(N2C3=CC=C(C#N)C(C(F)(F)F)=C3)=S)C(C)(C)C2=O)C=C1F
Molecular Formula
C20H13F4N3O3S
Molecular Weight
451.39
Precautions
H302, H315, H319, H335
References & Citations
[1]van Nuland M, et al. Exposure-Response Assessment of Enzalutamide and Its Major Metabolites in a Real-World Cohort of Patients with Metastatic Castration-Resistant Prostate Cancer. Pharmacotherapy. 2019 Dec;39 (12) :1137-1145.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
