5-APDI (hydrochloride)

5-APDI hydrochloride is an indane with an amphetamine-like aminopropane group. 5-APDI hydrochloride inhibits the uptake of serotonin, dopamine, and norepinephrine by crude synaptosomes (IC50 values of 82 nM, 1,847 nM, and 849 nM, respectively) [1].

Product Specifications

CAS Number

[152623-95-5]

UNSPSC

12352005

Target

5-HT Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/5-apdi-hydrochloride.html

Smiles

NC(CC1=CC=C2C(CCC2)=C1)C.Cl

Molecular Formula

C12H18ClN

Molecular Weight

211.73

References & Citations

[1]A P Monte, et al. Synthesis and pharmacological examination of benzofuran, indan, and tetralin analogues of 3,4- (methylenedioxy) amphetamine. J Med Chem. 1993 Nov 12;36 (23) :3700-6.