DL-dithiothreitol-d6
DL-dithiothreitol-d6 is the deuterated form of DL-dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. DL-dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond[1][2].
Product Specifications
CAS Number
[850153-85-4]
Product Name Alternative
DTT-d6
UNSPSC
12352100
Hazard Statement
H302, H315, H319, H335
Target
Disulfidptosis; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Cancer
Purity
99.0
Solubility
10 mM in DMSO|DMSO : 100mg/mL (ultrasonic)
Smiles
SC([2H])([2H])[C@](O)([2H])[C@@](O)([2H])C([2H])([2H])S
Molecular Formula
C4H4D6O2S2
Molecular Weight
160.29
Precautions
H302, H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Yao H, et al. Establishment of disulfidptosis-related LncRNA signature as biomarkers in colon adenocarcinoma[J]. Cancer Cell International, 2024, 24 (1) : 183.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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