DL-dithiothreitol-d6

DL-dithiothreitol-d6 is the deuterated form of DL-dithiothreitol. DL-dithiothreitol (DTT) is a strong reductant with anti-disulfidptosis activity. DL-dithiothreitol is oxidized to form a stable six-membered ring with an internal disulfide bond[1][2].

Product Specifications

CAS Number

[850153-85-4]

Product Name Alternative

DTT-d6

UNSPSC

12352100

Hazard Statement

H302, H315, H319, H335

Target

Disulfidptosis; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Field of Research

Cancer

Purity

99.0

Solubility

10 mM in DMSO|DMSO : 100mg/mL (ultrasonic)

Smiles

SC([2H])([2H])[C@](O)([2H])[C@@](O)([2H])C([2H])([2H])S

Molecular Formula

C4H4D6O2S2

Molecular Weight

160.29

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Yao H, et al. Establishment of disulfidptosis-related LncRNA signature as biomarkers in colon adenocarcinoma[J]. Cancer Cell International, 2024, 24 (1) : 183.