piCRAC-1
Product Specifications
UNSPSC Description
piCRAC-1 is a potent, photoinducible Ca2+ release-activated Ca2+ (CRAC) channel inhibitor. piCRAC-1 alleviates thrombocytopenia and hemorrhage[1].
Target Antigen
CRAC Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/picrac-1.html
Solubility
DMSO : ≥ 100 mg/mL
Smiles
FC(F)(F)C(C=CC=C1F)=C1CN2N=C(C=C2)/N=N/C3=C(C=CC=C3F)F
Molecular Weight
384.28
References & Citations
[1]Yang X, et al. Optical Control of CRAC Channels Using Photoswitchable Azopyrazoles. J Am Chem Soc. 2020 May 20;142(20):9460-9470.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-147005/piCRAC-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-147005/piCRAC-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2418049-54-2