PiCRAC-1

PiCRAC-1 is a potent, photoinducible Ca2+ release-activated Ca2+ (CRAC) channel inhibitor. piCRAC-1 alleviates thrombocytopenia and hemorrhage[1].

Product Specifications

CAS Number

[2418049-54-2]

UNSPSC

12352005

Target

CRAC Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/picrac-1.html

Purity

98.24

Solubility

DMSO : ≥ 100 mg/mL

Smiles

FC(F)(F)C(C=CC=C1F)=C1CN2N=C(C=C2)/N=N/C3=C(C=CC=C3F)F

Molecular Formula

C17H10F6N4

Molecular Weight

384.28

References & Citations

[1]Yang X, et al. Optical Control of CRAC Channels Using Photoswitchable Azopyrazoles. J Am Chem Soc. 2020 May 20;142 (20) :9460-9470.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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