PiCRAC-1
PiCRAC-1 is a potent, photoinducible Ca2+ release-activated Ca2+ (CRAC) channel inhibitor. piCRAC-1 alleviates thrombocytopenia and hemorrhage[1].
Product Specifications
CAS Number
[2418049-54-2]
UNSPSC
12352005
Target
CRAC Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/picrac-1.html
Purity
98.24
Solubility
DMSO : ≥ 100 mg/mL
Smiles
FC(F)(F)C(C=CC=C1F)=C1CN2N=C(C=C2)/N=N/C3=C(C=CC=C3F)F
Molecular Formula
C17H10F6N4
Molecular Weight
384.28
References & Citations
[1]Yang X, et al. Optical Control of CRAC Channels Using Photoswitchable Azopyrazoles. J Am Chem Soc. 2020 May 20;142 (20) :9460-9470.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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