TC-DAPK 6

TC-DAPK 6 is a potent, ATP-competitive, and highly selective DAPK inhibitor (IC50=69 and 225 nM against DAPK1 and DAPK3, respectively, with 10 μM ATP) .

Product Specifications

CAS Number

[315694-89-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

DAPK

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/TC-DAPK-6.html

Purity

96.87

Solubility

DMSO : 18.67 mg/mL (ultrasonic; warming)

Smiles

O=C(OC(/C=C/C1=CC=CC=C1)=N/2)C2=C/C3=CC=CN=C3

Molecular Formula

C17H12N2O2

Molecular Weight

276.29

Precautions

H302, H315, H319, H335

References & Citations

[1]Okamoto M, et al. Identification of death-associated protein kinases inhibitors using structure-based virtual screening. J Med Chem. 2009 Nov 26;52 (22) :7323-7.