N-Oleoyl serinol

N-Oleoyl serinol is a ceramide analog that can be used in stem cell therapy to prevent stem cells from developing into teratomas. N-Oleoyl serinol induces apoptosis in residual pluripotent embryoid body-derived cells (EBCs), prevents teratoma formation, and enriches EBC cells that undergo neural differentiation after transplantation[1].

Product Specifications

CAS Number

[72809-08-6]

Product Name Alternative

Oleoyl serinol

UNSPSC

12352211

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-oleoyl-serinol.html

Solubility

10 mM in DMSO

Smiles

CCCCCCCC/C=C\CCCCCCCC(NC(CO)CO)=O

Molecular Formula

C21H41NO3

Molecular Weight

355.56

References & Citations

[1]Bieberich E, et al. Selective apoptosis of pluripotent mouse and human stem cells by novel ceramide analogues prevents teratoma formation and enriches for neural precursors in ES cell-derived neural transplants. J Cell Biol. 2004 Nov 22;167 (4) :723-34.