N-Oleoyl serinol
N-Oleoyl serinol is a ceramide analog that can be used in stem cell therapy to prevent stem cells from developing into teratomas. N-Oleoyl serinol induces apoptosis in residual pluripotent embryoid body-derived cells (EBCs), prevents teratoma formation, and enriches EBC cells that undergo neural differentiation after transplantation[1].
Product Specifications
CAS Number
[72809-08-6]
Product Name Alternative
Oleoyl serinol
UNSPSC
12352211
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n-oleoyl-serinol.html
Solubility
10 mM in DMSO
Smiles
CCCCCCCC/C=C\CCCCCCCC(NC(CO)CO)=O
Molecular Formula
C21H41NO3
Molecular Weight
355.56
References & Citations
[1]Bieberich E, et al. Selective apoptosis of pluripotent mouse and human stem cells by novel ceramide analogues prevents teratoma formation and enriches for neural precursors in ES cell-derived neural transplants. J Cell Biol. 2004 Nov 22;167 (4) :723-34.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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