Human IFN-alpha 1 Protein, Fc Tag (MALS verified)
Human IFN-alpha 1, Fc Tag (IFA-H5258) is expressed from human 293 cells (HEK293) . It contains AA Cys 24 - Glu 189 (Accession # P01562-1) .
Product Specifications
Background
Interferon alpha-1 is also known as IFN-alpha-1/13, Interferon alpha-D, LeIF D and IFNA1, belongs to the alpha / beta interferon family. Interferons alpha-1 and alpha-13 have identical protein sequences. Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. IFN-alpha can either suppress or promote the development of autoimmune diabetes. It is likely that IFN-alpha plays a complex role in the etiology of type 1 diabetes.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 45.8 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P01562-1
Expression Region
Cys 24 - Glu 189
Host
HEK293
Target
IFN-alpha 1
Conjugation
Unconjugated
Tag
C-Fc
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Format
Powder
Buffer
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
45.8 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
1mg*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/IFA-H5258.pdf
Species
Human
Curated Selection
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