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Upacicalcet (sodium)

Product Specifications

UNSPSC Description

Upacicalcet sodium is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT)[1].

Target Antigen

CaSR

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/upacicalcet-sodium.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NC[C@H](N)C(O[Na])=O)NC1=CC(S(=O)(O)=O)=CC(Cl)=C1C

Molecular Weight

373.75

References & Citations

[1]Hoy SM. Upacicalcet: First Approval. Drugs. 2021;81(13):1593-1596.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-109106A/Upacicalcet-sodium-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-109106A/Upacicalcet-sodium-SDS-MedChemExpress.pdf

Clinical Information

Launched

CAS Number

2052969-18-1

Available Sizes

Curated Selection

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