Recombinant UBE2N Protein

<strong>Recombinant UBE2N Protein</strong>_x000D_ <strong>Catalog number:</strong> B2017766_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 19.30 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> Ubiquitin conjugating enzyme E2 N, HEL-S-71, UBC13, UbcH-Ben, UbcH13, UBCHBEN_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Zhang H, Cui Z, Cheng D, Du Y, Guo X, Gao R, Chen J, Sun W, He R, Ma X, Peng Q, Martin BN, Yan W, Rong Y, Wang C. RNF186 regulates EFNB1 (ephrin B1)-EPHB2-induced autophagy in the colonic epithelial cells for the maintenance of intestinal homeostasis Autophagy. 2021 Oct;17(10):3030-3047._x000D_ 2: Puvar K, Iyer S, Fu J, Kenny S, Negrón Terón KI, Luo ZQ, Brzovic PS, Klevit RE, Das C. Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination Nat Commun. 2020 May 12;11(1):2365._x000D_ 3: Sawasaki T, Endo Y. Cell-free-based protein microarray technology using agarose/DNA microplate Methods Mol Biol. 2010;607:63-72._x000D_ 4: Kobayashi J, Iwabuchi K, Miyagawa K, Sonoda E, Suzuki K, Takata M, Tauchi H. Current topics in DNA double-strand break repair J Radiat Res. 2008 Mar;49(2):93-103._x000D_ 5: Cheng J, Fan YH, Xu X, Zhang H, Dou J, Tang Y, Zhong X, Rojas Y, Yu Y, Zhao Y, Vasudevan SA, Zhang H, Nuchtern JG, Kim ES, Chen X, Lu F, Yang J. A small-molecule inhibitor of UBE2N induces neuroblastoma cell death via activation of p53 and JNK pathways Cell Death Dis. 2014 Feb 20;5(2):e1079._x000D_ 6: Kanao R, Masutani C. Regulation of DNA damage tolerance in mammalian cells by post-translational modifications of PCNA Mutat Res. 2017 Oct;803-805:82-88._x000D_ 7: Ni J, Guan C, Liu H, Huang X, Yue J, Xiang H, Jiang Z, Tao Y, Cao W, Liu J, Wang Z, Wang Y, Wu X. Ubc13 Promotes K63-Linked Polyubiquitination of NLRP3 to Activate Inflammasome J Immunol. 2021 May 15;206(10):2376-2385._x000D_ 8: Liwocha J, Krist DT, van der Heden van Noort GJ, Hansen FM, Truong VH, Karayel O, Purser N, Houston D, Burton N, Bostock MJ, Sattler M, Mann M, Harrison JS, Kleiger G, Ovaa H, Schulman BA. Linkage-specific ubiquitin chain formation depends on a lysine hydrocarbon ruler Nat Chem Biol. 2021 Mar;17(3):272-279._x000D_ 9: Masud T, Soong C, Xu H, Biele J, Bjornson S, McKinney S, Aparicio S. Ubiquitin-mediated DNA damage response is synthetic lethal with G-quadruplex stabilizer CX-5461 Sci Rep. 2021 May 7;11(1):9812._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/34070855">10: Liedtke V, Schröder C, Roggenbuck D, Weiss R, Stohwasser R, Schierack P, Rödiger S, Schenk L. LEDGF/p75 Is Required for an Efficient DNA Damage Response Int J Mol Sci. 2021 May 30;22(11):5866. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant UBE2N Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>