Nonivamide
Nonivamide is a agonist, which exhibits 4d-EC50 value of 5.1 mg/L in static toxicity tests.
Product Specifications
CAS Number
2444-46-4
Product Name Alternative
Pelargonic acid vanillylamide; Nonanoic acid vanillylamide; Pseudocapsaicin
UNSPSC
12352005
Hazard Statement
H301, H312, H315, H317, H318, H334, H335
Target
TRP Channel
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Nonivamide.html
Purity
99.06
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCCCCCCCC(NCC1=CC=C(O)C(OC)=C1)=O
Molecular Formula
C17H27NO3
Molecular Weight
293.40
Precautions
H301, H312, H315, H317, H318, H334, H335
References & Citations
[1]Zhou J, et al. Toxic effects of environment-friendly antifoulant Nonivamide on Phaeodactylum tricornutum. Environ Toxicol Chem. 2013 Apr;32 (4) :802-9.|[2]Thomas KC, et al. Transient receptor potential vanilloid 1 agonists cause endoplasmic reticulum stress and cell death in human lung cells. J Pharmacol Exp Ther. 2007 Jun;321 (3) :830-8.|[3]Rohm B, et al. Nonivamide enhances miRNA let-7d expression and decreases adipogenesis PPARγ expression in 3T3-L1 cells. J Cell Biochem. 2015 Jun;116 (6) :1153-63.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
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