Anti-PSA Antibody

Mouse Monoclonal Antibody specific to PSA

Product Specifications

CAS Number

9007-83-4

Product Name Alternative

PSA, EC 3.4.21.77, γ-seminoprotein, Seminin, Kallikrein-3, P-30 antigen, Semenogelase

Gene Name

KLK3

NCBI Gene ID

UniProt

P07288

Cellular Locus

Secreted.

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human PSA.

Target Antigen

Prostate-specific antigen

Target

PSA

Clonality

Monoclonal

Isotype

IgG1

Type

Antibody

Applications

IHC

Field of Research

Cancer research

Purification Method

Purified by immunoaffinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Tris

Function

Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.

Additionnal Information

<br><br>Immunohistochemistry: use at a dilution of 1:100-1:200 on formalin-fixed, paraffin-embedded samples after heat-induced epitope retrieval at pH 9 for 10-30 minutes.

Storage Conditions

Store at 2-8°C. Do not freeze.

Specificity

Human PSA. Reactivity with other species has not been investigated.

Formulation

Tris buffer, pH 7.3-7.7, 1% BSA, 0.1% sodium azide.

Buffer pH

pH 7.3-7.7

Target Background

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a glycoprotein enzyme encoded in humans by the KLK3 gene. PSA is a member of the kallikrein- related peptidase family and is secreted by the epithelial cells of the prostate gland. PSA is present in small quantities in the serum of men with healthy prostates but is often elevated in cases of prostate cancer or other prostate disorders.