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MAO-B-IN-31

MAO-B-IN-31 (Compound 30) is an effective and selective inhibitor of monoamine oxidase B (monoamine oxidase B) . The IC50 value is 41 nM. MAO-B-IN-31 also inhibits α-syn and tau aggregation. MAO-B-IN-31 has neuroprotective activity[1].

Product Specifications

UNSPSC

12352005

Target

α-synuclein

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/mao-b-in-31.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=NC2=CC=C(O)C=C2S1)NCCC3=CC=CC=C3

Molecular Formula

C16H14N2O2S

Molecular Weight

298.36

References & Citations

[1]Al-Saad O M, et al. Novel 6-hydroxybenzothiazol-2-carboxamides as potent and selective monoamine oxidase B inhibitors endowed with neuroprotective activity. European Journal of Medicinal Chemistry, 2024: 116266.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

α-synuclein Aggregation

Frequently Asked Questions

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