Apocynin-d3
Apocynin-d3 is the deuterium labeled Apocynin[1]. Apocynin is a selective NADPH-oxidase inhibitor with an IC50 of 10 μM[2][3][4].
Product Specifications
CAS Number
[80404-23-5]
Product Name Alternative
Acetovanillone-d3
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Apoptosis; Autophagy
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.85
Solubility
10 mM in DMSO
Smiles
[2H]C([2H])([2H])OC1=CC(C(C)=O)=CC=C1O
Molecular Formula
C9H7D3O3
Molecular Weight
169.19
Precautions
H315, H319, H335
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Stolk J, et al. Am J Respir Cell Mol Biol, 1994, 11 (1), 95-102.|[3]Stefanska J, et al. Mediators Inflamm, 2008, 106507.|[4]Impellizzeri D et al. Effect of apocynin, a NADPH oxidase inhibitor, on acute lung inflammation. Biochem Pharmacol. 2011 Mar 181 (5) :636-48.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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