Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Letosteine

Letosteine is an orally active, potent and safe expectorant. Letosteine has the effect of scavenging reactive oxygen species (ROS) . Letosteine dissolves bronchial mucus and reduces respiratory inflammation symptoms, and restores gas exchanges and natural defense mechanisms in the lung. Letosteine can be used for acute or chronic respiratory diseases (such as bronchopneumopathies) research[1][2][3][4].

Product Specifications

CAS Number

53943-88-7

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/letosteine.html

Purity

99.78

Solubility

DMSO : 11.11 mg/mL (ultrasonic; adjust pH to 12 with 1M NaOH)

Smiles

CCOC(CSCCC1NC(C(O)=O)CS1)=O

Molecular Formula

C10H17NO4S2

Molecular Weight

279.38

Precautions

H302, H315, H319, H335

References & Citations

[1]Jia L. Letosteine. John Wiley & Sons, Ltd, 2014.|[2]Macquet V, et al. A new contribution to the treatment of chronic bronchopneumopathies: letosteine. Lille Med. 1979;24 (9) :735-738.|[3]Zhou Y, et al. Efficacy and safety of letosteine in the treatment of sputum thickening and expectoration difficulty in patients with respiratory diseases: a multicenter, randomized, double-masked, double dummy, positive drug parallel controlled trial. Pharmazie. 2014;69 (11) :842-849.|[4]Gachon F, et al. Disposition and metabolism of letosteine in rats. Drug Metab Dispos. 1988;16 (6) :853-857.|[5]Gressier B, et al. Scavenging of reactive oxygen species by letosteine, a molecule with two blocked-SH groups. Comparison with free-SH drugs. Pharm World Sci. 1995 May 26;17 (3) :76-80.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Mouse Fibroblast Growth Factor 2, Basic (FGF2) ELISA Kit
RDR-FGF2-Mu-01 96 Tests

Mouse Fibroblast Growth Factor 2, Basic (FGF2) ELISA Kit

Sign In for Pricing
View Details
Mouse Fibroblast Growth Factor 2, Basic (FGF2) ELISA Kit
RDR-FGF2-Mu-02 48 Tests

Mouse Fibroblast Growth Factor 2, Basic (FGF2) ELISA Kit

Sign In for Pricing
View Details
PE Anti-Human CD226/DNAM-1 Antibody[11A8]
E-AB-F1369D-01 20 Tests

PE Anti-Human CD226/DNAM-1 Antibody[11A8]

Sign In for Pricing
View Details
PE Anti-Human CD226/DNAM-1 Antibody[11A8]
E-AB-F1369D-02 100 Tests

PE Anti-Human CD226/DNAM-1 Antibody[11A8]

Sign In for Pricing
View Details
PE Anti-Human CD226/DNAM-1 Antibody[11A8]
E-AB-F1369D-03 2x 100 Tests

PE Anti-Human CD226/DNAM-1 Antibody[11A8]

Sign In for Pricing
View Details
ErbB 3 (ERBB3) (NM_001005915) Human Over-expression Lysate
LC423671 20 µg

ErbB 3 (ERBB3) (NM_001005915) Human Over-expression Lysate

Sign In for Pricing
View Details