Dihydrocyclosporin A
Dihydrocyclosporin A is a derivative of Cyclosporine A. Dihydrocyclosporin A significantly inhibites promastigotes and intracellular amastigotes. Dihydrocyclosporin A is highly cytotoxic[1].
Product Specifications
CAS Number
59865-15-5
UNSPSC
12352209
Hazard Statement
H302, H350, H362
Target
Parasite
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dihydrocyclosporin-a.html
Solubility
10 mM in DMSO
Smiles
CCCC[C@@H](C)[C@H]([C@]1([H])N(C([C@@H](N(C([C@@H](N(C([C@@H](N(C([C@H](NC([C@@H](NC([C@@H](N(C([C@@H](NC([C@@H](N(C(CN(C([C@@H](NC1=O)CC)=O)C)=O)C)CC(C)C)=O)C(C)C)=O)C)CC(C)C)=O)C)=O)C)=O)C)CC(C)C)=O)C)CC(C)C)=O)C)C(C)C)=O)C)O
Molecular Formula
C62H113N11O12
Molecular Weight
1204.63
Precautions
H302, H350, H362
References & Citations
[1]Zheng ZW, et al. Evaluation of in vitro antileishmanial efficacy of cyclosporin A and its non-immunosuppressive derivative, dihydrocyclosporin A. Parasit Vectors. 2020 Feb 21;13 (1) :94.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature, keep dry and cool
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC550856-100 1x 100 µL
WT1 (Wilm's Tumor 1) (6F-H2), CF555 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC400665-500 1x 500 µL
Smooth Muscle Actin (1A4), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC881537-100 1x 100 µL
Beta-2 Microglobulin (Renal Failure &Tumor Marker) (rB2M/961), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680988-500 1x 500 µL
CD54 (W-CAM-1; same as Wehi-CAM-1 or 1H4), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880296-500 1x 500 µL
Blood Group Antigen B (CD173) (HEB-20), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details