Dihydrocyclosporin A

Dihydrocyclosporin A is a derivative of Cyclosporine A (HY-B0579) . Dihydrocyclosporin A significantly inhibites promastigotes and intracellular amastigotes. Dihydrocyclosporin A is highly cytotoxic[1].

Product Specifications

CAS Number

[59865-15-5]

UNSPSC

12352209

Hazard Statement

H302, H350, H362

Target

Parasite

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/dihydrocyclosporin-a.html

Solubility

10 mM in DMSO

Smiles

CCCC[C@@H](C)[C@H]([C@]1([H])N(C([C@@H](N(C([C@@H](N(C([C@@H](N(C([C@H](NC([C@@H](NC([C@@H](N(C([C@@H](NC([C@@H](N(C(CN(C([C@@H](NC1=O)CC)=O)C)=O)C)CC(C)C)=O)C(C)C)=O)C)CC(C)C)=O)C)=O)C)=O)C)CC(C)C)=O)C)CC(C)C)=O)C)C(C)C)=O)C)O

Molecular Formula

C62H113N11O12

Molecular Weight

1204.63

Precautions

H302, H350, H362

References & Citations

[1]Zheng ZW, et al. Evaluation of in vitro antileishmanial efficacy of cyclosporin A and its non-immunosuppressive derivative, dihydrocyclosporin A. Parasit Vectors. 2020 Feb 21;13 (1) :94.